Novamet
Metformin hydrochloride BP 500 mg
Metformin is a biguanide that exerts its effect mainly by decreasing gluconeogenesis and by increasing peripheral utilization of glucose.
Metformin decreases hepatic glucose production and intestinal absorption of glucose and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.
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1. Type 2 diabetes mellitus [monotherapy or in combination with other antidiabetic drugs (including insulin)]
2. Polycystic ovary syndrome
1. Type 2 diabetes mellitus [monotherapy or in combination with other antidiabetic drugs (including insulin)]
Child 10-17 years (Specialist use only) : Initially 500mg once daily, dose to be adjusted according to response at intervals of at least 1 week, maximum daily dose to be given 2-3 divided doses; maximum 2g per day or as directed by physcian.
Adult : Initially 500 mg once daily for at least 1 week, dose to be taken with breakfast, then 500mg twice daily for at least 1 week, dose to be taken with breakfast and evening meal, then 500 mg 3 times a day, dose to be taken with breakfast, lunch and evening meal; maximum 2g per day or as directed by physcian.
2. Polycystic ovary syndrome
Adult : Initially 500 mg once daily for 1 week, dose to be taken with breakfast, then 500mg twice daily for 1 week, dose to be taken with breakfast and evening meal, then 1.5-1.7g daily in 2-3 divided doses or as directed by physcian.
